#-*- coding: utf-8 -*- NvERTx Embryo-Regen plotter

Embryogenesis and Regeneration Co-Expression Clusters

Using fuzzy c-means clustering, we regrouped temporal expression patterns during embryonic development as well as during oral regeneration of Nematostella vectensis. Clicking on a cluster will display all associated genes . Ticking a checkbox in the table then 'Compare!' will bring you to the results page of that transcript.

References for regeneration and novel embryonic datasets: Warner et al(a), 2017, Warner et al(b), 2017. Re-analyzed embryonic datasets: Fischer et al. 2014,Tulin et al. 2013,and Helm et al. 2013

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Explore Mfuzz Clusters

Cluster E-1

Cluster E-2

Cluster E-3

Cluster E-4

Cluster E-5

Cluster E-6

Cluster E-7

Cluster E-8

Mfuzz cluster

Details

click on a row to view the other nr hits

ID mfuzz regen clust mfuzz regen score mfuzz embryo clust mfuzz embryo score Uniprot ID Uniprot description top nr_hit eval
NvERTx.4.135069 R-8 0.818841627031 E-6 0.854327167491 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.135070 R-8 0.818841627031 E-6 0.854327167491 No_Uniprotmatch No_Description gi|156359742|ref|XP_001624924.1|predicted protein [Nematostella vectensis], 1e-16
other nr_hits gi|1005442524|ref|XP_015758602.1|PREDICTED: rho guanine nucleotide exchange factor 28-like [Acropora digitifera] 1e-05;
NvERTx.4.135071 R-8 0.818841627031 E-6 0.854327167491 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.135072 R-8 0.818841627031 E-6 0.854327167491 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.135073 R-8 0.818841627031 E-6 0.854327167491 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.204740 R-8 0.818841627031 E-6 0.854327167491 No_Uniprotmatch No_Description gi|156359742|ref|XP_001624924.1|predicted protein [Nematostella vectensis], 1e-40
other nr_hits NA
NvERTx.4.204741 R-8 0.818841627031 E-6 0.854327167491 No_Uniprotmatch No_Description gi|156359742|ref|XP_001624924.1|predicted protein [Nematostella vectensis], 3e-34
other nr_hits NA
NvERTx.4.204742 R-8 0.818841627031 E-6 0.854327167491 Q6P9R4 Rho guanine nucleotide exchange factor 18 gi|156359742|ref|XP_001624924.1|predicted protein [Nematostella vectensis], 0e+00
other nr_hits gi|1005442524|ref|XP_015758602.1|PREDICTED: rho guanine nucleotide exchange factor 28-like [Acropora digitifera] 4e-167; gi|1005968717|ref|XP_015792139.1|PREDICTED: uncharacterized protein LOC107368771 [Tetranychus urticae] 1e-98; gi|443734806|gb|ELU18663.1|hypothetical protein CAPTEDRAFT_209220 [Capitella teleta] 2e-94; gi|919046473|ref|XP_013406410.1|PREDICTED: A-kinase anchor protein 13-like isoform X7 [Lingula anatina] 1e-92; gi|919046475|ref|XP_013406411.1|PREDICTED: rho guanine nucleotide exchange factor 28-like isoform X8 [Lingula anatina] 1e-92; gi|919046477|ref|XP_013406412.1|PREDICTED: rho guanine nucleotide exchange factor 28-like isoform X9 [Lingula anatina] 1e-92; gi|919046479|ref|XP_013406413.1|PREDICTED: rho guanine nucleotide exchange factor 28-like isoform X10 [Lingula anatina] 1e-92; gi|919046481|ref|XP_013406414.1|PREDICTED: rho guanine nucleotide exchange factor 28-like isoform X11 [Lingula anatina] 1e-92; gi|919046483|ref|XP_013406416.1|PREDICTED: rho guanine nucleotide exchange factor 28-like isoform X12 [Lingula anatina] 1e-92;
NvERTx.4.204743 R-8 0.818841627031 E-6 0.854327167491 No_Uniprotmatch No_Description gi|156359742|ref|XP_001624924.1|predicted protein [Nematostella vectensis], 3e-28
other nr_hits NA
NvERTx.4.204744 R-8 0.818841627031 E-6 0.854327167491 Q6P9R4 Rho guanine nucleotide exchange factor 18 gi|156359742|ref|XP_001624924.1|predicted protein [Nematostella vectensis], 0e+00
other nr_hits gi|1005442524|ref|XP_015758602.1|PREDICTED: rho guanine nucleotide exchange factor 28-like [Acropora digitifera] 3e-168; gi|1005968717|ref|XP_015792139.1|PREDICTED: uncharacterized protein LOC107368771 [Tetranychus urticae] 1e-98; gi|443734806|gb|ELU18663.1|hypothetical protein CAPTEDRAFT_209220 [Capitella teleta] 2e-94; gi|919046473|ref|XP_013406410.1|PREDICTED: A-kinase anchor protein 13-like isoform X7 [Lingula anatina] 1e-92; gi|919046475|ref|XP_013406411.1|PREDICTED: rho guanine nucleotide exchange factor 28-like isoform X8 [Lingula anatina] 1e-92; gi|919046477|ref|XP_013406412.1|PREDICTED: rho guanine nucleotide exchange factor 28-like isoform X9 [Lingula anatina] 1e-92; gi|919046479|ref|XP_013406413.1|PREDICTED: rho guanine nucleotide exchange factor 28-like isoform X10 [Lingula anatina] 1e-92; gi|919046481|ref|XP_013406414.1|PREDICTED: rho guanine nucleotide exchange factor 28-like isoform X11 [Lingula anatina] 1e-92; gi|919046483|ref|XP_013406416.1|PREDICTED: rho guanine nucleotide exchange factor 28-like isoform X12 [Lingula anatina] 1e-92;
NvERTx.4.12168 R-3 0.988232048892 E-6 0.853054233998 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.12169 R-3 0.988232048892 E-6 0.853054233998 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.113395 R-3 0.988232048892 E-6 0.853054233998 No_Uniprotmatch No_Description gi|156384817|ref|XP_001633329.1|predicted protein [Nematostella vectensis], 5e-34
other nr_hits gi|999978552|gb|KXJ17726.1|Glutamine-rich protein 2 [Exaiptasia pallida] 2e-14;
NvERTx.4.113396 R-3 0.988232048892 E-6 0.853054233998 No_Uniprotmatch No_Description gi|156384817|ref|XP_001633329.1|predicted protein [Nematostella vectensis], 9e-38
other nr_hits gi|999978552|gb|KXJ17726.1|Glutamine-rich protein 2 [Exaiptasia pallida] 1e-26;
NvERTx.4.113397 R-3 0.988232048892 E-6 0.853054233998 No_Uniprotmatch No_Description gi|156384817|ref|XP_001633329.1|predicted protein [Nematostella vectensis], 2e-07
other nr_hits NA
NvERTx.4.113398 R-3 0.988232048892 E-6 0.853054233998 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.113399 R-3 0.988232048892 E-6 0.853054233998 Q9H0J4 Glutamine-rich protein 2 gi|156384817|ref|XP_001633329.1|predicted protein [Nematostella vectensis], 2e-235
other nr_hits gi|999978552|gb|KXJ17726.1|Glutamine-rich protein 2 [Exaiptasia pallida] 2e-172; gi|585677755|ref|XP_006819197.1|PREDICTED: putative uncharacterized protein C16orf96-like [Saccoglossus kowalevskii] 1e-36; gi|1005472297|ref|XP_015773016.1|PREDICTED: uncharacterized protein C16orf96 homolog [Acropora digitifera] 9e-36; gi|1005428830|ref|XP_015752148.1|PREDICTED: glutamine-rich protein 2-like [Acropora digitifera] 2e-34; gi|999969203|gb|KXJ08377.1|Glutamine-rich protein 2 [Exaiptasia pallida] 8e-34; gi|1139809999|ref|XP_019924672.1|PREDICTED: nuclease SbcCD subunit C isoform X2 [Crassostrea gigas] 9e-33; gi|1121869738|ref|XP_019398196.1|PREDICTED: glutamine-rich protein 2 isoform X4 [Crocodylus porosus] 2e-32; gi|1121869729|ref|XP_019398194.1|PREDICTED: glutamine-rich protein 2 isoform X2 [Crocodylus porosus] 2e-32; gi|1121869723|ref|XP_019398193.1|PREDICTED: glutamine-rich protein 2 isoform X1 [Crocodylus porosus] 2e-32;
NvERTx.4.113400 R-3 0.988232048892 E-6 0.853054233998 Q9H0J4 Glutamine-rich protein 2 gi|156384817|ref|XP_001633329.1|predicted protein [Nematostella vectensis], 2e-235
other nr_hits gi|999978552|gb|KXJ17726.1|Glutamine-rich protein 2 [Exaiptasia pallida] 2e-172; gi|585677755|ref|XP_006819197.1|PREDICTED: putative uncharacterized protein C16orf96-like [Saccoglossus kowalevskii] 1e-36; gi|1005472297|ref|XP_015773016.1|PREDICTED: uncharacterized protein C16orf96 homolog [Acropora digitifera] 9e-36; gi|1005428830|ref|XP_015752148.1|PREDICTED: glutamine-rich protein 2-like [Acropora digitifera] 2e-34; gi|999969203|gb|KXJ08377.1|Glutamine-rich protein 2 [Exaiptasia pallida] 8e-34; gi|1139809999|ref|XP_019924672.1|PREDICTED: nuclease SbcCD subunit C isoform X2 [Crassostrea gigas] 9e-33; gi|1121869738|ref|XP_019398196.1|PREDICTED: glutamine-rich protein 2 isoform X4 [Crocodylus porosus] 2e-32; gi|1121869729|ref|XP_019398194.1|PREDICTED: glutamine-rich protein 2 isoform X2 [Crocodylus porosus] 2e-32; gi|1121869723|ref|XP_019398193.1|PREDICTED: glutamine-rich protein 2 isoform X1 [Crocodylus porosus] 2e-32;
NvERTx.4.90513 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.94877 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.94878 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.94879 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.94880 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.94881 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171566 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171567 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171568 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171569 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171571 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171572 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171573 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171557 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171576 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171577 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171558 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171559 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171560 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171562 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171563 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.171565 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.188985 R-5 0.61542790163 E-6 0.852936423771 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.144872 R-5 0.621848573571 E-6 0.852511672269 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.118456 R-3 0.986006409986 E-6 0.852486965604 Q8BSM7 Large neutral amino acids transporter small subunit 3 gi|156369839|ref|XP_001628181.1|predicted protein [Nematostella vectensis], 2e-192
other nr_hits gi|156380824|ref|XP_001631967.1|predicted protein [Nematostella vectensis] 8e-59; gi|291228960|ref|XP_002734445.1|PREDICTED: large neutral amino acids transporter small subunit 4-like [Saccoglossus kowalevskii] 7e-24; gi|1126158153|ref|XP_019637717.1|PREDICTED: large neutral amino acids transporter small subunit 4-like isoform X4 [Branchiostoma belcheri] 6e-22; gi|1126158157|ref|XP_019637902.1|PREDICTED: solute carrier family 43 member 3-like isoform X2 [Branchiostoma belcheri] 8e-22; gi|1126158155|ref|XP_019637832.1|PREDICTED: solute carrier family 43 member 3-like isoform X1 [Branchiostoma belcheri] 8e-22; gi|1126158149|ref|XP_019637550.1|PREDICTED: large neutral amino acids transporter small subunit 4-like isoform X2 [Branchiostoma belcheri] 7e-21; gi|1126158151|ref|XP_019637625.1|PREDICTED: large neutral amino acids transporter small subunit 4-like isoform X3 [Branchiostoma belcheri] 3e-20; gi|961989962|ref|XP_014825902.1|PREDICTED: large neutral amino acids transporter small subunit 3 [Poecilia mexicana] 3e-20; gi|260834201|ref|XP_002612100.1|hypothetical protein BRAFLDRAFT_104816 [Branchiostoma floridae] 3e-20;
NvERTx.4.118457 R-3 0.986006409986 E-6 0.852486965604 Q8NBI5 Solute carrier family 43 member 3 gi|156369839|ref|XP_001628181.1|predicted protein [Nematostella vectensis], 4e-251
other nr_hits gi|156380824|ref|XP_001631967.1|predicted protein [Nematostella vectensis] 6e-74; gi|1129960496|ref|XP_019739955.1|PREDICTED: solute carrier family 43 member 3-like [Hippocampus comes] 3e-32; gi|942203874|ref|XP_014353408.1|PREDICTED: solute carrier family 43 member 3 [Latimeria chalumnae] 2e-31; gi|831543713|ref|XP_012725619.1|PREDICTED: solute carrier family 43 member 3-like isoform X2 [Fundulus heteroclitus] 3e-31; gi|975104558|ref|XP_015267572.1|PREDICTED: solute carrier family 43 member 3 [Gekko japonicus] 2e-30; gi|902887391|ref|XP_013033268.1|PREDICTED: solute carrier family 43 member 3 isoform X2 [Anser cygnoides domesticus] 5e-30; gi|1126158153|ref|XP_019637717.1|PREDICTED: large neutral amino acids transporter small subunit 4-like isoform X4 [Branchiostoma belcheri] 1e-29; gi|971397957|ref|XP_003641425.3|PREDICTED: solute carrier family 43 member 3 isoform X2 [Gallus gallus] 1e-29; gi|529440680|ref|XP_005240080.1|PREDICTED: solute carrier family 43 member 3 isoform X4 [Falco peregrinus] 2e-29;
NvERTx.4.118458 R-3 0.986006409986 E-6 0.852486965604 Q8BSM7 Large neutral amino acids transporter small subunit 3 gi|156369839|ref|XP_001628181.1|predicted protein [Nematostella vectensis], 1e-167
other nr_hits gi|156380824|ref|XP_001631967.1|predicted protein [Nematostella vectensis] 3e-48; gi|1126158153|ref|XP_019637717.1|PREDICTED: large neutral amino acids transporter small subunit 4-like isoform X4 [Branchiostoma belcheri] 9e-18; gi|1126158149|ref|XP_019637550.1|PREDICTED: large neutral amino acids transporter small subunit 4-like isoform X2 [Branchiostoma belcheri] 1e-16; gi|1126158151|ref|XP_019637625.1|PREDICTED: large neutral amino acids transporter small subunit 4-like isoform X3 [Branchiostoma belcheri] 4e-16; gi|961989962|ref|XP_014825902.1|PREDICTED: large neutral amino acids transporter small subunit 3 [Poecilia mexicana] 4e-16; gi|1129960496|ref|XP_019739955.1|PREDICTED: solute carrier family 43 member 3-like [Hippocampus comes] 1e-15; gi|617443320|ref|XP_007565915.1|PREDICTED: large neutral amino acids transporter small subunit 3 [Poecilia formosa] 1e-15; gi|961979434|ref|XP_014871261.1|PREDICTED: large neutral amino acids transporter small subunit 3 [Poecilia latipinna] 2e-15; gi|1126158157|ref|XP_019637902.1|PREDICTED: solute carrier family 43 member 3-like isoform X2 [Branchiostoma belcheri] 2e-15;
NvERTx.4.118459 R-3 0.986006409986 E-6 0.852486965604 Q8NBI5 Solute carrier family 43 member 3 gi|156369839|ref|XP_001628181.1|predicted protein [Nematostella vectensis], 5e-57
other nr_hits gi|156380824|ref|XP_001631967.1|predicted protein [Nematostella vectensis] 4e-10; gi|942203874|ref|XP_014353408.1|PREDICTED: solute carrier family 43 member 3 [Latimeria chalumnae] 1e-06; gi|830031590|ref|XP_012580507.1|PREDICTED: solute carrier family 43 member 3 isoform X2 [Condylura cristata] 2e-06; gi|507950353|ref|XP_004683521.1|PREDICTED: solute carrier family 43 member 3 isoform X1 [Condylura cristata] 2e-06; gi|984085292|ref|XP_015333425.1|PREDICTED: solute carrier family 43 member 3 isoform X3 [Marmota marmota marmota] 2e-06; gi|984085282|ref|XP_015333419.1|PREDICTED: solute carrier family 43 member 3 isoform X1 [Marmota marmota marmota] 2e-06; gi|984085290|ref|XP_015333424.1|PREDICTED: solute carrier family 43 member 3 isoform X2 [Marmota marmota marmota] 2e-06; gi|47215688|embl|CAG04772.1|unnamed protein product [Tetraodon nigroviridis] 2e-06; gi|831543709|ref|XP_012725618.1|PREDICTED: solute carrier family 43 member 3-like isoform X1 [Fundulus heteroclitus] 2e-06;
NvERTx.4.118460 R-3 0.986006409986 E-6 0.852486965604 Q8NBI5 Solute carrier family 43 member 3 gi|156369839|ref|XP_001628181.1|predicted protein [Nematostella vectensis], 1e-250
other nr_hits gi|156380824|ref|XP_001631967.1|predicted protein [Nematostella vectensis] 4e-86; gi|291228960|ref|XP_002734445.1|PREDICTED: large neutral amino acids transporter small subunit 4-like [Saccoglossus kowalevskii] 3e-36; gi|942203874|ref|XP_014353408.1|PREDICTED: solute carrier family 43 member 3 [Latimeria chalumnae] 3e-34; gi|1129960496|ref|XP_019739955.1|PREDICTED: solute carrier family 43 member 3-like [Hippocampus comes] 4e-34; gi|831543713|ref|XP_012725619.1|PREDICTED: solute carrier family 43 member 3-like isoform X2 [Fundulus heteroclitus] 5e-34; gi|1126158153|ref|XP_019637717.1|PREDICTED: large neutral amino acids transporter small subunit 4-like isoform X4 [Branchiostoma belcheri] 2e-33; gi|975104558|ref|XP_015267572.1|PREDICTED: solute carrier family 43 member 3 [Gekko japonicus] 2e-33; gi|974090874|ref|XP_015243675.1|PREDICTED: solute carrier family 43 member 3-like [Cyprinodon variegatus] 1e-32; gi|260834201|ref|XP_002612100.1|hypothetical protein BRAFLDRAFT_104816 [Branchiostoma floridae] 1e-32;
NvERTx.4.118461 R-3 0.986006409986 E-6 0.852486965604 Q8BSM7 Large neutral amino acids transporter small subunit 3 gi|156369839|ref|XP_001628181.1|predicted protein [Nematostella vectensis], 3e-226
other nr_hits gi|156380824|ref|XP_001631967.1|predicted protein [Nematostella vectensis] 2e-63; gi|1129960496|ref|XP_019739955.1|PREDICTED: solute carrier family 43 member 3-like [Hippocampus comes] 9e-29; gi|942203874|ref|XP_014353408.1|PREDICTED: solute carrier family 43 member 3 [Latimeria chalumnae] 1e-26; gi|831543713|ref|XP_012725619.1|PREDICTED: solute carrier family 43 member 3-like isoform X2 [Fundulus heteroclitus] 4e-26; gi|975104558|ref|XP_015267572.1|PREDICTED: solute carrier family 43 member 3 [Gekko japonicus] 9e-26; gi|1126158153|ref|XP_019637717.1|PREDICTED: large neutral amino acids transporter small subunit 4-like isoform X4 [Branchiostoma belcheri] 2e-25; gi|1007710840|ref|XP_015827368.1|PREDICTED: solute carrier family 43 member 3-like [Nothobranchius furzeri] 6e-25; gi|902887391|ref|XP_013033268.1|PREDICTED: solute carrier family 43 member 3 isoform X2 [Anser cygnoides domesticus] 6e-25; gi|831543709|ref|XP_012725618.1|PREDICTED: solute carrier family 43 member 3-like isoform X1 [Fundulus heteroclitus] 8e-25;
NvERTx.4.118463 R-3 0.986006409986 E-6 0.852486965604 No_Uniprotmatch No_Description None
other nr_hits NA
NvERTx.4.118464 R-3 0.986006409986 E-6 0.852486965604 No_Uniprotmatch No_Description gi|156369839|ref|XP_001628181.1|predicted protein [Nematostella vectensis], 7e-107
other nr_hits gi|1005470097|ref|XP_015771931.1|PREDICTED: uncharacterized protein LOC107350222 isoform X1 [Acropora digitifera] 3e-35; gi|1005494378|ref|XP_015749817.1|PREDICTED: uncharacterized protein LOC107329662 isoform X1 [Acropora digitifera] 1e-33; gi|1005494380|ref|XP_015749818.1|PREDICTED: uncharacterized protein LOC107329662 isoform X2 [Acropora digitifera] 5e-33; gi|1005444609|ref|XP_015759646.1|PREDICTED: uncharacterized protein LOC107338906 [Acropora digitifera] 9e-33; gi|1005470099|ref|XP_015771933.1|PREDICTED: uncharacterized protein LOC107350222 isoform X2 [Acropora digitifera] 2e-27; gi|1005423193|ref|XP_015770444.1|PREDICTED: uncharacterized protein LOC107348872 isoform X3 [Acropora digitifera] 6e-27; gi|1005423191|ref|XP_015770436.1|PREDICTED: uncharacterized protein LOC107348872 isoform X2 [Acropora digitifera] 2e-26; gi|1005486312|ref|XP_015779756.1|PREDICTED: uncharacterized protein LOC107357628 [Acropora digitifera] 3e-26; gi|1005446288|ref|XP_015760442.1|PREDICTED: uncharacterized protein LOC107339641 [Acropora digitifera] 6e-24;
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